This knowledge will translate directly into significant and measurable social and economic benefits for Canada.
CHILD will have a direct impact on public health-based prevention strategies for:
- asthma and allergic diseases; environmental exposure regulations and policies;
- safe home product standards and regulations;
- food safety regulations and policies;
- urban planning and home design;
- maternal-child health;
- prenatal care (diet, nutrition) guidelines;
- pediatric allergy and asthma guidelines; and,
- novel therapeutic targets for drug discovery and exposure modulation.
The CHILD Study has recruited over 3500 families !
Expectant mothers, most of whom in their second trimester, have been recruited from the general population in several areas in Canada including: Vancouver, British Columbia; Edmonton, Alberta; Manitoba (Winnipeg and 2 rural sites); and Toronto, Ontario. The children and their mothers are monitored throughout the remainder of pregnancy and until the babies reach 5 years of age.
- All children will be clinically assessed at:
- at a 3-month home visit, and
- at ages 1, 3, and 5 years.
- Home assessment with dust sample collection at 3 months is complemented by repeated detailed environmental questionnaires from pregnancy to age 5.
- Anthropometric measures, pulmonary function and viral infections are assessed longitudinally.
- Biological sampling includes:
- genetic material from the child and parents,
- cord blood,
- breast-milk at 3 months,
- infant peripheral blood at 1 and 5 years,
- viral swabs,
- urine and stool at multiple time points, and
- Questionnaire data will be collected on pre- and post-natal environment, nutrition, stress, health status and medication.